German Haemapheresis Centre

REFERENCES CYTAPHERESIS

TECHNIQUE

Shibusawa, J
Separation and retention of human blood cells by surface affinity chromatography
J Biochem BiophysMethods 2001; 49 (1-3): 683 - 703
Shibusawa, J
Surface affinity chromatography of human peripheral blood cells.
J Chromatogr B Biomed Sci Appl 1999; 722 (1-2): 71 - 88
Yamayi, K, Tsuda, H, Hashimoto, H
Current topics on cytapheresis technologies
Ther Apher 2001; 5 (4):287 - 292
Yui, N, Samui, K, Ogata, N, Kataoka, K Okano, T, Sakurai, Y
Reversibility of granulocyte adhesion using polyamine - grafted nylon - 6 as a new column substrate for granulocyte separation.
Biomaterials 1985; 6 (6): 409 - 415
Shirokaze, J
Leukocytapheresis using a leukocyte removal filter.
Ther Apher 2002; 6 (4): 261 - 266
Kawamura, A, Saitoh, M, Yonekawa, M, Horie, T, Ohizumi, H, Tamaki, T, Kukita, K, Meguro J
New technique of leukocytapheresis by the use of nonwoven polyester filter for inflammatory bowel disease.
Ther Apher 1999; 3(4): 334 - 337
Ayabe, T, Ashida, T, Kohgo, Y
Centrifugal leukocytapheresis for ulcerative colitis
Ther Apher 1998; 2(2): 125 - 128
Ito, Y, Shinomiya, K
A new continuous flow separation method based on cell density : Principle, apparatus,and preliminary application to separation of human buffy coat.
J Clin Apher 2001; 16:186 - 191

THERAPEUTIC ERYTHROCYTAPHERESIS

1. General

Blaha M, Skorepova M, Masin V, Spasova I, Parakova Z, Maly J, Zak P, Belada D, Turkova A.
The role of erythrocytapheresis in secondary erythrocytosis therapy.
Clin Hemorheol Microcirc. 2002;26(4):273 - 275
Borberg H, Brunner R, Tauchert M, Widder R.
The current state of extracorporeal haemorheotherapy: from haemodilution via cascadefiltration to rheohaemapheresis.
Transfus Apheresis Sci. 2001;24(1):57 - 64
Hollan SR.
Transfusion-associated iron overload.
Curr Opin Hematol. 1997 Nov;4(6):436-41. Review
Adams DM, Schultz WH, Ware RE, Kinney TR.
Erythrocytapheresis can reduce iron overload and prevent the need for chelation therapy in chronically transfused pediatric patients.
J Pediatr Hematol Oncol. 1996;18(1):46 - 50
Ilhan O, Uskent N, Arslan O, Arat M, Ozkalemkas F, Ozturk G, Kalayoglu SB, Ozet A, Tombuloglu M, Arpaci F, Ovali E, Anak S.
National survey of hemapheresis practice in Turkey (1998).
Transfus Sci. 2000;22(3):195 - 201
Valbonesi M, Bruni R.
Clinical application of therapeutic erythrocytapheresis (TEA).
Transfus Sci. 2000;22(3):183 - 94
Gorlin JB.
Therapeutic plasma exchange and cytapheresis in pediatric patients.
Transfus Sci. 1999;21(1): 21 - 39

2. Sickle Cell Disease

Kirkham FJ, DeBaun MR.
Stroke in Children with Sickle Cell Disease.
Curr Treat Options Neurol. 2004;6(5): 357 - 375
Raj A, Bertolone SJ, Mangold S, Edmonds HL Jr.
Assessment of cerebral tissue oxygenation in patients with sickle cell disease: effect of transfusion therapy.
J Pediatr Hematol Oncol. 2004;26(5): 279 - 283
Koduri PR.
Iron in sickle cell disease: a review why less is better.
Am J Hematol. 2003;73(1): 59 - 63
Nifong TP, Domen RE.
Oxygen saturation and hemoglobin A content in patients with sickle cell disease undergoing erythrocytapheresis.
Ther Apher. 2002;6(5): 390 - 933
Henderson JN, Noetzel MJ, McKinstry RC, White DA, Armstrong M, DeBaun MR.
Reversible posterior leukoencephalopathy syndrome and silent cerebral infarcts are associated with severe acute chest syndrome in children with sickle cell disease.
Blood. 2003; 15;101(2):415 - 419
Hartwig D, Schlager F, Bucsky P, Kirchner H, Schlenke P.
Successful long-term erythrocytapheresis therapy in a patient with symptomatic sickle-cell disease using an arterio-venous fistula.
Transfus Med. 2002;12(1):75 - 77
Nifong TP, Bongiovanni MB, Gerhard GS.
Mathematical modeling and computer simulation of erythrocytapheresis for SCD.
Transfusion. 2001;41(2): 256 - 263
Singer ST, Quirolo K, Nishi K, Hackney-Stephens E, Evans C, Vichinsky EP.
Erythrocytapheresis for chronically transfused children with sickle cell disease: an effective method for maintaining a low hemoglobin S level and reducing iron overload.
J Clin Apheresis. 1999;14(3): 122 - 125
Hilliard LM, Williams BF, Lounsbury AE, Howard TH.
Erythrocytapheresis limits iron accumulation in chronically transfused sickle cell patients.
Am J Hematol. 1998;59(1): 28 - 35
Kim HC, Dugan NP, Silber JH, Martin MB, Schwartz E, Ohene-Frempong K, Cohen AR.
Erythrocytapheresis therapy to reduce iron overload in chronically transfused patients with sickle cell disease.
Blood. 1994; 15;83(4): 1136 - 1142
Lee W, Werch J, Rokey R, Pivarnik J, Miller J.
Physiologic observations of pregnant women undergoing prophylactic erythrocytapheresis for sickle cell disease.v Transfusion. 1991;31(1): 59 - 62
Morrison JC, Morrison FS, Floyd RC, Roberts WE, Hess LW, Wiser WL.
Use of continuous flow erythrocytapheresis in pregnant patients with sickle cell disease. J Clin Apheresis. 1991;6(4): 224 - 229
Froehly S, Diemunsch P, Waller C, Renaud R, Gros H.
Use of erythrocytapheresis in a pregnant woman with sickle cell anemia Ann Fr Anesth Reanim. 1989;8(1): 67 - 69.

3. Haemochromatosis

Power TE, Adams PC.
Hemochromatosis patients as voluntary blood donors
Can J Gastroenterol 2004; 18,(6): 393 - 396
Muncunill J, Vaquer P, Galmes A, Obrador A, Parera M, Bargay J, Besalduch J.
In hereditary hemochromatosis, red cell apheresis removes excess iron twice as fast as manual whole blood phlebotomy.
J Clin Apheresis. 2002;17(2): 88 - 92
Kohan A, Niborski R, Daruich J, Rey J, Bastos F, Amerise G, Herrera R, Garcia M, Olivera W, Santarelli MT, Avalos JS, Findor J.
Erythrocytapheresis with recombinant human erythropoietin in hereditary hemochromatosis therapy: a new alternative.
Vox Sang. 2000;79(1): 40 - 45
Adams PC.
Prevalence of abnormal iron studies in heterozygotes for hereditary hemochromatosis: an analysis of 255 heterozygotes.
Am J Hematol. 1994;45(2): 146 - 149
Kellner H, Zoller WG.
Repeated isovolemic large-volume erythrocytapheresis in the treatment of idiopathic hemochromatosis.
Z Gastroenterol. 1992;30(11): 779 - 783
Fraquelli M, Mandelli C, Cesarini L, Barisani D, Bianchi PA, Conte D.
Survival and development of neoplasms in 56 patients with idiopathic hemochromatosis Ann Ital Med Int. 1992;7(1):26 - 29
Kaboth U, Rumpf KW, Lipp T, Bigge J, Nauck M, Beyer JH, Seyde W, Kaboth W.
Treatment of polycythemia vera by isovolemic large-volume erythrocytapheresis. Klin Wochenschr. 1990 4;68(1): 18 - 25
Likhovetskaia ZM, Prigozhina TA, Gorbunova NA, Kalinin NN, Petrov MM.
Blood rheologic disorders in patients with polycythemia vera and their correction by therapeutic erythrocytapheresis
Gematol Transfuziol. 1989;34(11): 33 - 36
Cesana M, Mandelli C, Tiribelli C, Bianchi PA, Conte D.
Concomitant primary hemochromatosis and beta-thalassemia trait: iron depletion by erythrocytapheresis and desferrioxamine.
Am J Gastroenterol. 1989;84(2): 150 - 152
Conte D, Mandelli C, Cesana M, Ferrini R, Marconi M, Bianchi A.
Effectiveness of erythrocytapheresis in idiopathic hemochromatosis. Report of 14 cases.
Int J Artif Organs. 1989 ;12(1): 59 - 62
Zoller WG, Kellner H,Spengel FA.
Erythrocytapheresis. A method for rapid extracorporeal elimination of erythrocytes.
Klein Wschr 1988; 66(9): 404 - 409
Batey RG, Hussein S, Sherlock S, Hoffbrand AV.
The role of serum ferritin in the management of idiopathic haemochromatosis.
Scand J Gastroenterol. 1978;13(8): 953 - 957

4. Polycythaemia vera

Kaboth U, Rumpf KW, Liersch T, Vehmeyer K, Krieter D, Kaboth W.
Advantages of isovolemic large-volume erythrocytapheresis as a rapidly effective and long-lasting treatment modality for red blood cell depletion in patients with polycythemia vera.
Ther Apher. 1997;1(2): 131 - 134
Liersch T, Vehmeyer K, Kaboth U.
Related Articles, Links Large volume, isovolemic erythrocytapheresis in treatment of polycythemia vera. Effect of massive iron depletion of proliferation behavior of erythroid precursor cells (BFU-E)
Med Klin (Munich). 1995 15;90(7): 390 - 397. Erratum in: Med Klin 1995 15;90(9): 554
Bessmel'tsev SS, Zamotina TB.
Effects of erythrocytopheresis on the state of the left heart in patients with polycythemia vera: echocardiographic findings
Klin Med (Mosk). 1995;73(4): 80 - 82
Kaboth U, Rumpf KW, Lipp T, Bigge J, Nauck M, Beyer JH, Seyde W, Kaboth W.
Treatment of polycythemia vera by isovolemic large-volume erythrocytapheresis.
Klin Wochenschr. 1990 4;68(1): 18 - 25

5. Infectious diseases

Zhang Y, Telleria L, Vinetz JM, Yawn D, Rossmann S, Indrikovs AJ.
Erythrocytapheresis for Plasmodium falciparum infection complicated by cerebral malaria and hyperparasitemia.
J Clin Apheresis. 2001;16(1): 15 - 18
Macallan DC, Pocock M, Robinson GT, Parker-Williams J, Bevan DH.
Red cell exchange, erythrocytapheresis, in the treatment of malaria with high parasitaemia in returning travellers.
Trans R Soc Trop Med Hyg. 2000;94(4): 353 - 356
Macallan DC, Pocock M, Bishop E, Bevan DH, Parker-Williams J, Harrison T, Robinson GT.
Automated erythrocytapheresis in the treatment of severe falciparum malaria.
J Infect. 1999;39(3): 233 - 236

6. Cor pulmonale

Bisaga W.
Preliminary evaluation of erythrapheresis in the treatment of chronic cor pulmonale
Wiad Lek. 1989; 42(4): 218 - 222
Froehly S, Diemunsch P, Waller C, Renaud R, Gros H.
Use of erythrocytapheresis in a pregnant woman with sickle cell anemia
Ann Fr Anesth Reanim. 1989;8(1): 67 - 69

7. Other

Werch J, Todd C.
Resolution by erythrocytapheresis of the exposure of an Rh-negative person to Rh-positive cells: an alternative treatment.
Transfusion. 1993 ;33(6): 530 - 532
Schooneman F, Streiff F, Ribon M, Boutroy JL, Rumilly F.
Erythropheresis in 4 cases of congenital hemolytic anemia
Ann Med Interne (Paris). 1988;139 Suppl 1:18 - 19

DONOR ERYTHROCYTAPHERESIS

Power TE, Adams PC.
Hemochromatosis patients as voluntary blood donors
Can J Gastroenterol 2004; 18,(6): 393 - 396
Kalfon F, Beaumont JL, Fournel JJ, Viars P.
Transfusional strategy in neurosurgery: preoperative hemodilution by erythrocytapheresis
Ann Fr Anesth Reanim. 1994;13(6):798-806.
Larson PJ, Friedman DF, Reilly MP, Kattamis AC, Asakura T, Fortina P, Cohen AR, Kim HC, Manno CS.
The presurgical management with erythrocytapheresis of a patient with a high-oxygen-affinity, unstable Hb variant (Hb Bryn Mawr).
Transfusion. 1997 ; 37(7): 703 - 707
Laubriat-Bianchin M.
Preoperative autologous erythrocytapheresis
Ann Fr Anesth Reanim. 1995;14 Suppl 1:47-52
Beaumont JL.
Does preoperative erythroapheresis avoid homologous transfusion?
Transfus Clin Biol. 1994;1(3): 209 - 213

LEUKOCYTAPHERESIS

DONOR GRANULOZYTAPHERESIS FOR GRANULOCYTE TRANSFUSION

Borberg H
Zelluläre Substitution
in Gross, R, Schmidt, CG (Hrsg.)
Georg Thieme Verlag 1985: 20.20
Bux, J, Cassens, U, Dielschneider, T, Duchscherer, M, Edel, E, Eichler, H, Haas, C, Moog, R, Peschke, H, Peters, C, Ryzenkov, I, Schlenke, P, Ullrich, H, Wiesneth, M.
Tolerance of granulocyte donors towards granulocyte colony-stimulating factor stimulation and of patients towards granulocyte transfusions:Results of a multicentre study.
Vox Sang 2003; 85 (4): 322 - 325
Bashir, S, Cardigan, R
Granulocyte concentrates:How can we assess their quality ? Transfus med 2003; 13 (5): 245 - 258
Briones, MA, Josephson, CD, Hillyer, CD
Granulocyte transfusion revisited.
Curr Hematol Rep 2003; 2(6): 522 - 527
Hester, JP, Dignani, MC, Anaissie, NJ, Kantarjian, HM, O'Brien, S. Freireich, EJ
Collection and transfusion of granulocyte concentrates from donors primed with granulocyte stimulating factor and response of myelosuppressed patients with established infections.
J Clin Apher 1995; 10: 188 - 193

MONOZYTAPHERESIS AND DENDRITIC CELLS

Faradji, A, Bohbot, A, Schmitt-Goguel, M, Siffert, JC, Dumont S,Wi ? , ML, Piemont, Y, Eischen, A, Bergerat, JP, Bartholeyns, J
Large scale Isolation of human blood monocytes by continuous flow centrifugation leukapheresis and counterflow centrifugal elutriation for adoptive cellular immunotherapy of cancer patients
J. Immunol.Methods 1994; 174 (1-2): 297 - 309
Dowling, R, Webe,r V, Osborne, L, Klein, H
Mononuclear cell collection using various techniques
J. Clin.Apheresis 1984; 2 (1):32 - 40
Sorg, RV, Brefort, Th, Fischer, J, Ackermann, R, Wernet, P
Clinical scale generation of dendritic cells in a closed system.
Abstract, 7th Internatl. Symposium on Dendritic Cells, Sept. 19 - 24, 2002, Bamberg (Germany)

DENDRITIC CELLS

Sorg, R, Brefort, Th, Fischer, J, Ackermann, R, Wernet, P
Clinical scale generation of dendritic cells in a closed system.
7th Intl Symposium on Dendritic Cells, Sept 19 - 24, 2002, Bamberg (Germany) P 186
Chui,SY, Clay, TM, Hobeika, AC, Venturi, CB Osada, T, Khan, S, Colling, K, Mosca, PJ, Lyerly, HK, Morse, MA
Dendritic cell vaccination following high dose chemotherapy with autologous stem cell support for breast cancer: Long term follow up
ASCO, 2003, Abstract No. 682
Gluckman, JC, Canque, B, Chapuis, F, Rosenzwajg, M
In vitro generation of human dendritic cells and cell therapy
Cytokines Cell Mol Ther 1997; 3 (3): 187 - 196
Ardavin, C, Martinez delHoyo G, Martin P, Anjuerre, F, Arias, CF, Ruiz, S, Parrilas, V, Hernandez H
Origin and differentiation of dendritic cells.
Trends Immunol 2001; 22 (12): 691 - 700
Cella, M, Sallusto, F, Lanzavecchia A
Origin, maturation and antigen presenting function of dendritic cells.
Curr Opin Immunol 1997; 9 (1): 10 - 16
Labeur, MS, Roters, B, Pers, B, Mehling, A, Luger, TA, Schwarz,T, Grabbe, S
Generation of tumour immunity by bone marrow derived dendritic cells correlates with dendritic cell maturation. J Immunol 1999; 162 (1): 168 - 175
Meierhoff, G, Krause, SW, Andreesen, R
Comparative analysis of dendritic cells derived from blood monocates or CD 34+ haematopoietic progenitor cells.
Immunobiology 1998; 198 (5): 501 - 513
Zhou, LJ, Tedder, Th F
CD 14 + blood monocytes can differentiate into functionally mature CD 83+ dendritic cells
Proc.Natl.Acad.Sci. (USA) 1996; 93: 2588 - 2592
Grabbe S, Kampgen E, Schuler G.
Dendritic cells: multi-lineal and multi-functional.
Immunol Today. 2000 ; 21 (9): 431-3.
Nolte A, Scheffold C, Slotty J, Huenefeld C, Schultze JL, Grabbe S, Berdel WE, Kienast J.
Generation of melanoma-specific cytotoxic T lymphocytes for allogeneic immunotherapy.
J Immunother. 2003; 26 (3): 257 - 269
Gunzer M, Grabbe S.
Dendritic cells in cancer immunotherapy.
Crit Rev Immunol. 2001;21(1-3):133-45
Gunzer M, Janich S, Varga G, Grabbe S.
Dendritic cells and tumor immunity.
Semin Immunol. 2001; 13 (5): 291-302
Moron G, Rueda P, Casal I, Leclerc C.
CD8alpha- CD11b+ dendritic cells present exogenous virus-like particles to CD8+ T cells and subsequently express CD8alpha and CD205 molecules.
J. Exp. Med. 2002; 195: 1233 - 1245
Ikeda, Y, Akbar, SM, Matsui, H, Onji, M
Antigen presenting dendritic cells in ulcerative colitis
J Gastroenterol 2002; 37 (Suppl.14): 53 - 55
Ikeda, Y, Akbar, SM Matsui, H, Onji, M
Depletion an decreased function of antigen - presenting dendritic cells caused by lymphocytapheresis in ulcerative colitis.
Dis Colon Rectum 2003; 46 (4): 521 - 528
Ikeda, Y, Akbar, SM Matsui, H, Onji, M
Characterization of antigen presenting dendritic cells in the peripheral blood and colonic mucosa of patients with ulcerative colitis.v Eur J Gastroenterlol Hepatol 2001; 13 (7): 841 - 850

THERAPEUTIC LEUKOCYTAPHERESIS

COLITIS ULCEROSA

Dendritic cells

Ikeda, Y, Akbar, SM, Matsui, H, Onji, M
Antigen presenting dendritic cells in ulcerative colitis
J Gastroenterol 2002; 37 (Suppl.14): 53 - 55
Ikeda, Y, Akbar, SM Matsui, H, Onji, M
Depletion an decreased function of antigen - presenting dendritic cells caused by lymphocytapheresis in ulcerative colitis.
Dis Colon Rectum 2003; 46 (4): 521 - 528
Ikeda, Y, Akbar, SM Matsui, H, Onji, M
Characterization of antigen presenting dendritic cells in the peripheral blood and colonic mucosa of patients with ulcerative colitis.
Eur J Gastroenterlol Hepatol 2001; 13 (7): 841 - 850

Pathogenesis Pathogenese

Tsukada, Y, Nakamura, T, Iimura, M, Iizuka, BE, Hayashi, N
Cytokine profile in colonic mucosa of ulcerative colitis correlates with disease activity and response to granulocytapheresis
Am J Gastroenterol 2002; 97 (11):2820 - 2828
Squarcia, O, Fais, S, Boirivant, M, DiPaolo, MC, Marcheggiano, A, Iannoni, C, Paoluzi, P, Pallone, F
Phenotypes and spontaneous immunoglobulin production in mononuclear cells suspensions isolated from colonic biopsies of patients with mild active and quiescent ulcerative colitis
Gastroenterol Clin Biol 1991; 15(3): 194 - 198
Mitsuyama, K, Toyonaga, A, Sasaki, E, Watanabe, K, tateishi, H, Nishiyama, T, Saiki, T, Ikeda, H, Tsuruta, O, Tanikawa, K
Il-8 as an important chemoattractant for neutrophils in ulcerative colitis and Crohn's disease Clin Exp Immunol1994! 96(3):432 - 436
Sawada, K, Muto, T, Shimoyama, T, Satomi, M, Sawada, T, Nagawa,I, Hiwatashi, N, Asakura, H, Hibi, T
Multicenter randomized controlled trial from the treatment of ulcerative colitis with a leukocytapheresis column.
Curr Pharm Des 2003: 9 (4): 307 - 321
Shirokaze, J
Leukocytapheresis using a leukocyte removal filter
Ther Apher 2002; 6 (4): 261 - 266
Kondo, K, Shinoda, T, Yoshimoto, H, Takazoe, M, Hamada, T
Effective maintenance leukocytapheresis for patients with steroid dependent or resistant ulcerative colitis.
Ther Apher2001; 5 (6): 462 - 465
Kohgo, Y, Hibi, H, Chiba, T, Shimoyama, T, Muto, T, Yamamura, K, Popovsky, MA
Leukocyte apheresis using a centrifugal cell separator in refractory ulcerative colitis: A multicenter open label trial.
2002; 6 (4): 255 - 260
Shimoyama, T, Sawada, K, Hiwatashi, N, Sawada, T, Matsueda, K, Manakata, A, Asakura, H, Tanaka, T, Kasukawa, R, Kimura, K, Suzuki, Y, Nagamachi, Y, Muto, T, Nagawa, H, Iizuka, B, Baba, S, Nasu, M, Kataoka, K, Kashiwagi, N, saniabi, AR
Safety and efficacy of granulocyte and monocyte adsorption apheresis in patients with active ulcerative colitis: A multicenter study.
J Clin Apheresis 2001; 16 (1): 1 - 9

MORBUS CROHN

Rembacken, BJ, Newbould, HE, Richards, SJ, Misbah, SA, Dixon, ME, Chalmers, DM, Axon, AT
Granulocyte apheresis in inflammatory bowel disease: Possible mechanism of effect
Ther Apher 1998; 2 (2); 93 - 96
Matsui, T, Nishimura, T, Matake, H, Ohta, T, Sakurai, T, Yao, T
Granulocytapheresis for Crohn's disease: A report of seven refractory patients.
Am J Gastroenterol 2003; 98 (2): 511 - 512

Glomerulonephritis

Nakamura, T, Suzuki, Y, Koide, H
Granulocyte and monocyte adsorption apheresis in a patient with antiglomerular basement membrane glomerulonephritis and active ulcerative colitis
Am J Med Sci 2003; 325 (5): 296 - 298