German Haemapheresis Centre

and

German Apheresis Research Centre

Catalogue of therapeutic applications

Please note:
The degree of evidence of the treatments listed is variable.
Prior to the treatment the transferring physician and the apheresis specialist should establish a communication.
Not all applicable or indicated therapies are reimbursed from public health insurances!

Medical field or indication

Ophthalmology

Age related macular degeneration (preferentially dry form)
Diabetic retinopathy
Central vein thrombosis, Prestasis syndrom
Uveal effusion syndrome
Further experimental therapies may be discussed



Surgery

Severe sepsis
Diabetic foot
Peripheral arterial occlusion disease
Transplant rejection - antibody mediated
Transplant rejection - cell mediated



Dermatology

Mycosis fungoides (cutaneous T-cell lymphoma)
Pemphigus vulgaris
Bullous pemphigoid



Gynaecology and Obstetrics

Anti-phospholipid antibody syndrom


Otology

Acute deafness (sudden hearing loss)
Chronic relapsing hearing loss
Tinnitus


Immunology

Antibody mediated (auto-) immunopathies
Immune complex mediated (auto-) immunopathies
Vasculitis


Internal Medicine - Angiology

Diabetic foot
Peripheral arterial occlusive disease
ANCA positive Vasculitis
Raynaud's syndrome


Internal Medicine - Haematology

Haemochromatosis
Polycythaemia vera
Autoimmune haemolytic anaemia (AHXA)
Sickle cell anaemia
Thalassaemia
Platelet replacement during Myelosuppression with thrombozytopenia
Idiopathic Thrombocytosis
Idiopathic thrombocytopenic purpura (ITP)
Myelosuppression with sepsis
Leukaemias (AML,CML,CLL)
Periphereal blood stem cell transplantation Tumorimmunotherapy
AB= incompatible transplant rejection
- s. Transplantation
Hyperviscosity syndrome (Waldenström's disease, Plasmozytoma)
Thrombotic-thrombocytopenic purpura
Posttransfusion purpura
Haemolytic-uraemic syndrom (HUS)
Chemotherapy related intoxication
Cryoglobulinaemia
Haemophilia with antibody (I, VIII, IX, V)


Internal Medicine - Intensive care

Non dialysable intoxications
Other emergencies of internal medicine


Internal Medicine - Cardiology

Small vessel disease
Therapy refractory coronary heart disease
Pulmonal hypertonia
Eisenmenger complex and other cardial malformations
Diabetic cardiomyopathy
Autoimmune dilatative cardiomyopathy


Internal Medicine - Nephrology

Goodpasture's syndrome
Rapid progressive glomerulonephritis
(M. Wegener, lupus nephritis)
Fokal sclerosing glomerulonephritis (FSGN)
Transplantat rejection
- s. Transplantation



Internal Medicine - Pulmonology

Pulmonary fibrosis
Therapy refractory status asthmaticus
Goodpasture's syndrome


Internal Medicine - Rheumatology

Acute refractory polyarthritis
Sjögren's syndrome
Refractor5y systemic lupus erythomatosus (SLE)


Internal Medicine - Metabolic diseases and Endocrinology

Thyreotoxic crisis
Endocrine orbitopathy (malign exophtalamus)
Acute pancreatitis with hypertriglyceridaemia
(Diabetes, HLP type IV or V)
Familial hypercholesterinaemia type IIa
Excessive LP(a) elevation (especially in combination with hypercholesterolaemia)
Refsum's syndrome


Neurology

Myasthenia gravis
Lambert-Eaton syndrome
Neuromyotonia (Isaacs syndrome) Acute Guillain Barré syndrome
Chronic (autoimmune) demyelating polyneuropathy
Transitoric ischaemic attack (TIA)
Paraproteinaemic peripheral neuropathy
Miller-Fisher syndrome


Paediatrics

Paediatric Haematology
- s. Internal Medicine - Haematology

Paediatric Cardiology
- Cardiac malformation not accessible for surgery
- Eisenmenger's syndrome

Paediatric Nephrology
- s. Internal Medicine - Nephrology


Transplantation

Transplant rejection - vascular
Transplant rejection - cell mediated
AB0 incompatible transplant rejection
Allotransplantation
Xenotransplantation
Photopheresis therapy